Worthington
Worthington Biochemical Corporation is a leading supplier of high-quality enzymes and biochemicals, renowned for their commitment to excellence and innovation in the field of enzymatic research and applications. With a rich history of over 70 years, Worthington has established itself as a trusted partner for researchers and industries worldwide, providing reliable and effective solutions for a wide range of scientific needs.
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Product Portfolio
Worthington offers an extensive catalog of enzymes and biochemicals, including collagenases, deoxyribonucleases, and proteases, among others. Their products are meticulously developed to meet the highest standards of purity and performance, ensuring optimal results in various applications such as cell isolation, tissue dissociation, and molecular biology research.
Collagenase
Worthington's collagenases are renowned for their effectiveness in tissue dissociation and cell isolation applications. They offer a variety of types, each tailored to specific tissue types and research needs. For instance, Type 1 collagenase provides a balanced mix of enzymatic activities suitable for epithelial and liver tissues, while Type 4 is designed with low tryptic activity to minimize damage to membrane proteins, making it ideal for pancreatic islet isolation.
Deoxyribonuclease I (DNase I)
Worthington's DNase I is a high-purity enzyme used extensively in molecular biology for the removal of DNA from RNA preparations. This enzyme is available in various grades, including recombinant forms that are free from RNase and protease contaminants, ensuring the integrity of your RNA samples. It is particularly useful in applications such as RT-PCR and Northern blotting.
Proteases
Worthington offers a diverse range of proteases, including trypsin, papain, and elastase, each suited for different applications. Trypsin is widely used for protein digestion and sequencing, while papain is favored for its gentle action in neural tissue dissociation. Elastase is another key enzyme, often used in conjunction with collagenase for effective tissue dissociation. These products are developed under stringent quality controls and are available in both animal-free and traditional formulations, catering to the diverse needs of researchers and bioprocessing applications. Worthington's commitment to providing high-quality, reliable enzymes makes them a preferred choice for scientists worldwide.
Want to know more about the offerings from Worthington?
Explore Worthington's insightful Product Highlights , which focuses on tissue dissociation and enzyme applications. These guides cover various topics, including collagenase, DNase I, Proteinase K, and trypsin, offering valuable information on enzyme selection, storage, and application techniques. Whether you're a seasoned researcher or new to the field, these guides provide essential knowledge to enhance your research outcomes.
The document outlines collagenase enzymes from Clostridium histolyticum, detailing Type I and Type II enzymes for tissue dissociation and cell isolation. It highlights the importance of selecting the right type for specific applications and offers animal-free options to avoid animal-derived pathogens.
The Enzyme Digestion flyer features enzymes for tissue dissociation, such as papain, trypsin, and various collagenase types. It emphasizes the importance of enzyme selection based on digestive strength and application needs.
The Product Highlight document highlights various DNase I products, including recombinant and bovine pancreas-derived options. It emphasizes their high purity, being free from RNase and protease, and offers both lyophilized and solution forms. It also details storage conditions and activity levels to help you select the right DNase I for your research.
The product highlight document details Proteinase K, a serine endopeptidase with broad activity. It emphasizes the enzyme's stability across a wide pH range and its ability to remain active in the presence of SDS or urea. Additionally, it specifies storage conditions and offers both lyophilized and liquid formulations, making it suitable for various applications in isolating DNA and RNA.
The product highlight paper on trypsin describes it as a pancreatic serine protease with specificity for lysine and arginine. It details the enzyme's purification to remove contaminants and improve stability, offering both native and modified sequencing-grade forms. The paper also covers storage conditions and various applications, such as tissue culture and protein sequencing.
The product highlight document on cell isolation outlines various enzymes and protocols used for tissue dissociation and cell isolation. It emphasizes the importance of selecting the right enzyme combinations to maximize cell yield and viability. The paper also provides guidance on optimizing isolation procedures for different tissue types.
Worthington products in our webshop
Browse products from Worthington on our webshop. Our webshop offers a robust search function that lets you quickly find products by name or catalog number. You can view detailed product information, including specifications, data sheets, and customer specific prices.
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